Klinik und Poliklinik für Neurologie

Publikationen 2015

Fischer A, Schneider A, Wullner U. Epigenetic Mechanisms in Neurodegenerative Diseases AKTUEL NEUROL. 2015;42(7): 393-401 (Impact: liegt nicht vor, Typ=Review)

Jessen F, Klockgether T. Alzheimer Disease and Spinocerebellar Ataxias AKTUEL NEUROL. 2015;42(7): 411-417 (Impact: liegt nicht vor, Typ=Review)

Klockgether T. Current Research in the German Centre for Neurodegenerative Diseases (DZNE) AKTUEL NEUROL. 2015;42(7): 383-384 (Impact: liegt nicht vor, Typ=Editorial Material)

Rosengarten B, Heneka MT, Axer H. Current Aspects of Sepsis Therapy on Neurointensive Care Units Part 2: Sepsis-Related Encephalopathy AKTUEL NEUROL. 2015;42(3): 148-U60 (Impact: liegt nicht vor, Typ=Article)

Traschutz A, Heneka MT. Neuroinflammation in Neurodegenerative Disease AKTUEL NEUROL. 2015;42(7): 402-410 (Impact: liegt nicht vor, Typ=Review)

Thal DR, Walter J, Saido TC, Fändrich M. Neuropathology and biochemistry of A? and its aggregates in Alzheimer's disease. Acta Neuropathol (Berl). 2015;129(2): 167-82 (Impact(2014)=10.762, Typ=Review; Journal Article; Review; Research Support, Non-U.S. Gov't)

Balakrishnan K, Rijal Upadhaya A, Steinmetz J, Reichwald J, Abramowski D, Fändrich M, Kumar S, Yamaguchi H, Walter J, Staufenbiel M, Thal DR. Impact of amyloid ? aggregate maturation on antibody treatment in APP23 mice. Acta Neuropathol Commun. 2015;3: 41 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Bernis ME, Babila JT, Breid S, Wüsten KA, Wüllner U, Tamgüney G. Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein. Acta Neuropathol Commun. 2015;3(1): 75 (Impact: liegt nicht vor, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Mitsui J, Matsukawa T, Sasaki H, Yabe I, Matsushima M, Dürr A, Brice A, Takashima H, Kikuchi A, Aoki M, Ishiura H, Yasuda T, Date H, Ahsan B, Iwata A, Goto J, Ichikawa Y, Nakahara Y, Momose Y, Takahashi Y, Hara K, Kakita A, Yamada M, Takahashi H, Onodera O, Nishizawa M, Watanabe H, Ito M, Sobue G, Ishikawa K, Mizusawa H, Kanai K, Hattori T, Kuwabara S, Arai K, Koyano S, Kuroiwa Y, Hasegawa K, Yuasa T, Yasui K, Nakashima K, Ito H, Izumi Y, Kaji R, Kato T, Kusunoki S, Osaki Y, Horiuchi M, Kondo T, Murayama S, Hattori N, Yamamoto M, Murata M, Satake W, Toda T, Filla A, Klockgether T, Wüllner U, Nicholson G, Gilman S, Tanner CM, Kukull WA, Stern MB, Lee VM, Trojanowski JQ, Masliah E, Low PA, Sandroni P, Ozelius LJ, Foroud T, Tsuji S. Variants associated with Gaucher disease in multiple system atrophy. Ann Clin Transl Neurol. 2015;2(4): 417-26 (Impact: liegt nicht vor, Typ=Article; Journal Article)

Heneka MT, Fink A, Doblhammer G. Effect of pioglitazone medication on the incidence of dementia. Ann Neurol. 2015;78(2): 284-94 (Impact(2014)=9.977, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't; Observational Study)

Singer OC, Berkefeld J, Nolte CH, Bohner G, Haring HP, Trenkler J, Gröschel K, Müller-Forell W, Niederkorn K, Deutschmann H, Neumann-Haefelin T, Hohmann C, Bussmeyer M, Mpotsaris A, Stoll A, Bormann A, Brenck J, Schlamann MU, Jander S, Turowski B, Petzold GC, Urbach H, Liebeskind DS, ENDOSTROKE Study Group. Mechanical recanalization in basilar artery occlusion: the ENDOSTROKE study. Ann Neurol. 2015;77(3): 415-24 (Impact(2014)=9.977, Typ=Article; Journal Article; Clinical Trial; Multicenter Study; Observational Study)

Hong GS, Schwandt T, Stein K, Schneiker B, Kummer MP, Heneka MT, Kitamura K, Kalff JC, Wehner S. Effects of macrophage-dependent peroxisome proliferator-activated receptor ? signalling on adhesion formation after abdominal surgery in an experimental model. Br J Surg. 2015;102(12): 1506-16 (Impact(2014)=5.542, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Doeser A, Dickhof G, Reitze M, Uebachs M, Schaub C, Pires NM, Bonifácio MJ, Soares-da-Silva P, Beck H. Targeting pharmacoresistant epilepsy and epileptogenesis with a dual-purpose antiepileptic drug. Brain. 2015;138(Pt 2): 371-87 (Impact(2014)=9.196, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Klockgether T. Does degeneration of the subthalamic nucleus prevent parkinsonism in spinocerebellar ataxia type 2 and type 3? Brain. 2015;138(Pt 11): 3139-40 (Impact(2014)=9.196, Typ=Editorial Material; Journal Article; Comment)

Kurzwelly D, Krüger S, Biskup S, Heneka MT. A distinct clinical phenotype in a German kindred with motor neuron disease carrying a CHCHD10 mutation. Brain. 2015;138(Pt 9): e376 (Impact(2014)=9.196, Typ=Letter; Comment; Letter)

Stefanescu MR, Dohnalek M, Maderwald S, Thürling M, Minnerop M, Beck A, Schlamann M, Diedrichsen J, Ladd ME, Timmann D. Structural and functional MRI abnormalities of cerebellar cortex and nuclei in SCA3, SCA6 and Friedreich's ataxia. Brain. 2015;138(Pt 5): 1182-97 (Impact(2014)=9.196, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Shi Y, Wang C, Huang F, Chen Z, Sun Z, Wang J, Tang B, Ashizawa T, Klockgether T, Jiang H. High Serum GFAP Levels in SCA3/MJD May Not Correlate with Disease Progression. Cerebellum. 2015;14(6): 677-81 (Impact(2014)=2.717, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Zaremba S, Mueller N, Heisig AM, Shin CH, Jung S, Leffert LR, Bateman BT, Pugsley LJ, Nagasaka Y, Moreno Duarte I, Ecker JL, Eikermann M. Elevated upper body position improves pregnancy-related OSA without impairing sleep quality or sleep architecture early after delivery. Chest. 2015;148(4): 936-44 (Impact(2014)=7.483, Typ=Article; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't)

Weller M, Tabatabai G, Kästner B, Felsberg J, Steinbach JP, Wick A, Schnell O, Hau P, Herrlinger U, Sabel MC, Wirsching HG, Ketter R, Bähr O, Platten M, Tonn JC, Schlegel U, Marosi C, Goldbrunner R, Stupp R, Homicsko K, Pichler J, Nikkhah G, Meixensberger J, Vajkoczy P, Kollias S, Hüsing J, Reifenberger G, Wick W, DIRECTOR Study Group. MGMT Promoter Methylation Is a Strong Prognostic Biomarker for Benefit from Dose-Intensified Temozolomide Rechallenge in Progressive Glioblastoma: The DIRECTOR Trial. Clin Cancer Res. 2015;21(9): 2057-64 (Impact(2014)=8.722, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Kaut O, Schmitt I, Hofmann A, Hoffmann P, Schlaepfer TE, Wüllner U, Hurlemann R. Aberrant NMDA receptor DNA methylation detected by epigenome-wide analysis of hippocampus and prefrontal cortex in major depression. Eur Arch Psychiatry Clin Neurosci. 2015;265(4): 331-41 (Impact(2014)=3.525, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Lindlau A, Widmann CN, Putensen C, Jessen F, Semmler A, Heneka MT. Predictors of hippocampal atrophy in critically ill patients. Eur J Neurol. 2015;22(2): 410-5 (Impact(2014)=4.055, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Schmidt R, Hofer E, Bouwman FH, Buerger K, Cordonnier C, Fladby T, Galimberti D, Georges J, Heneka MT, Hort J, Laczó J, Molinuevo JL, O'Brien JT, Religa D, Scheltens P, Schott JM, Sorbi S. EFNS-ENS/EAN Guideline on concomitant use of cholinesterase inhibitors and memantine in moderate to severe Alzheimer's disease. Eur J Neurol. 2015;22(6): 889-98 (Impact(2014)=4.055, Typ=Article; Journal Article; Review; Meta-Analysis)

Galldiks N, Dunkl V, Stoffels G, Hutterer M, Rapp M, Sabel M, Reifenberger G, Kebir S, Dorn F, Blau T, Herrlinger U, Hau P, Ruge MI, Kocher M, Goldbrunner R, Fink GR, Drzezga A, Schmidt M, Langen KJ. Diagnosis of pseudoprogression in patients with glioblastoma using O-(2-[18F]fluoroethyl)-L-tyrosine PET. Eur J Nucl Med Mol Imaging. 2015;42(5): 685-95 (Impact(2014)=5.383, Typ=Article; Journal Article)

Glebov K, Löchner M, Jabs R, Lau T, Merkel O, Schloss P, Steinhäuser C, Walter J. Serotonin stimulates secretion of exosomes from microglia cells. Glia. 2015;63(4): 626-34 (Impact(2014)=6.031, Typ=Article; Journal Article)

Koppara A, Frommann I, Polcher A, Parra MA, Maier W, Jessen F, Klockgether T, Wagner M. Feature Binding Deficits in Subjective Cognitive Decline and in Mild Cognitive Impairment. J Alzheimers Dis. 2015;48 Suppl 1: S161-70 (Impact(2014)=4.151, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Lovestone S, Boada M, Dubois B, Hüll M, Rinne JO, Huppertz HJ, Calero M, Andrés MV, Gómez-Carrillo B, León T, del Ser T, ARGO investigators , Fernández M, Pérez de las Heras S, Alom J, Sola D, Sánchez-Valle R, Molinuevo JL, LLadó A, Baquero M, Bosca M, Gõni M, Prieto R, Frank A, López-Arrieta J, Sáenz C, Bermejo F, Sánchez-Ferro A, Gil P, Viloria A, Carreras MT, Gago A, Olazarán J, Cuello JP, Antúnez C, Marín J, Boada M, Lafuente A, Hernandez I, Reñé R, Campdelacreu J, Gascón J, Lá?nez JM, Santonja JM, Kulisevsky J, Villa C, Dubois B, Andrade K, Leder S, Ceccaldi M, Gúeriot C, Auriacombe S, Doireau M, Hugon J, Dumurguier J, Touchon J, Bennys K, Vercelletto M, Boutoleau-Bretonniere C, Rouaud O, Béjot Y, Hommet C, Camus V, Pariente J, Puel M, Ousset PJ, Sastre-Hengan N, Pasquier F, Bombois S, Belliard S, Michel O, Robert P, Mulin E, Lovestone S, Scoper T, Dale M, Govindraj S, Ratcliffe S, Asher A, Timmis H, MacWilliam C, Jones R, Gifford J, Passmore P, Larner A, Ritchie C, Raymont V, Wilkinson D, Sharples R, Bowie P, Hutchinson J, Bullock R, Keatings L, Adelman S, Wright L, Inglis F, Lynch J, Hüll M, Heimbach B, Prinz B, Steinwachs KC, Steib-Marauschat E, Kluenemann HH, Mendoza MC, Gertz HJ, Eggers B, Bodenschatz R, Troger J, Heneka M, Kurzwelly D, Thomsen J, Schulze A, Kurz A, Grimmer T, Rinne J, Rinne R, Soinninen H, Halikainen M, Pitkala K, Strandberg T, Remes A, Keskinarkaus I. A phase II trial of tideglusib in Alzheimer's disease. J Alzheimers Dis. 2015;45(1): 75-88 (Impact(2014)=4.151, Typ=Article; Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II; Research Support, Non-U.S. Gov't)

Meiberth D, Scheef L, Wolfsgruber S, Boecker H, Block W, Träber F, Erk S, Heneka MT, Jacobi H, Spottke A, Walter H, Wagner M, Hu X, Jessen F. Cortical thinning in individuals with subjective memory impairment. J Alzheimers Dis. 2015;45(1): 139-46 (Impact(2014)=4.151, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Krauthausen M, Kummer MP, Zimmermann J, Reyes-Irisarri E, Terwel D, Bulic B, Heneka MT, Müller M. CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model. J Clin Invest. 2015;125(1): 365-78 (Impact(2014)=13.262, Typ=Article; Journal Article)

Kinfe TM, Pintea B, Muhammad S, Zaremba S, Roeske S, Simon BJ, Vatter H. Cervical non-invasive vagus nerve stimulation (nVNS) for preventive and acute treatment of episodic and chronic migraine and migraine-associated sleep disturbance: a prospective observational cohort study. J Headache Pain. 2015;16: 101 (Impact(2014)=2.801, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Doss S, Rinnenthal JL, Schmitz-Hübsch T, Brandt AU, Papazoglou S, Lux S, Maul S, Würfel J, Endres M, Klockgether T, Minnerop M, Paul F. Cerebellar neurochemical alterations in spinocerebellar ataxia type 14 appear to include glutathione deficiency. J Neurol. 2015;262(8): 1927-35 (Impact(2014)=3.377, Typ=Article; Journal Article)

Marek M, Paus S, Allert N, Mädler B, Klockgether T, Urbach H, Coenen VA. Ataxia and tremor due to lesions involving cerebellar projection pathways: a DTI tractographic study in six patients. J Neurol. 2015;262(1): 54-8 (Impact(2014)=3.377, Typ=Article; Journal Article)

Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T, Vitorica J, Ransohoff RM, Herrup K, Frautschy SA, Finsen B, Brown GC, Verkhratsky A, Yamanaka K, Koistinaho J, Latz E, Halle A, Petzold GC, Town T, Morgan D, Shinohara ML, Perry VH, Holmes C, Bazan NG, Brooks DJ, Hunot S, Joseph B, Deigendesch N, Garaschuk O, Boddeke E, Dinarello CA, Breitner JC, Cole GM, Golenbock DT, Kummer MP. Neuroinflammation in Alzheimer's disease. Lancet Neurol. 2015;14(4): 388-405 (Impact(2014)=21.896, Typ=Review; Journal Article; Review)

Jacobi H, du Montcel ST, Bauer P, Giunti P, Cook A, Labrum R, Parkinson MH, Durr A, Brice A, Charles P, Marelli C, Mariotti C, Nanetti L, Panzeri M, Rakowicz M, Sulek A, Sobanska A, Schmitz-Hübsch T, Schöls L, Hengel H, Baliko L, Melegh B, Filla A, Antenora A, Infante J, Berciano J, van de Warrenburg BP, Timmann D, Szymanski S, Boesch S, Kang JS, Pandolfo M, Schulz JB, Molho S, Diallo A, Klockgether T. Long-term disease progression in spinocerebellar ataxia types 1, 2, 3, and 6: a longitudinal cohort study. Lancet Neurol. 2015;14(11): 1101-8 (Impact(2014)=21.896, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Reetz K, Dogan I, Costa AS, Dafotakis M, Fedosov K, Giunti P, Parkinson MH, Sweeney MG, Mariotti C, Panzeri M, Nanetti L, Arpa J, Sanz-Gallego I, Durr A, Charles P, Boesch S, Nachbauer W, Klopstock T, Karin I, Depondt C, vom Hagen JM, Schöls L, Giordano IA, Klockgether T, Bürk K, Pandolfo M, Schulz JB. Biological and clinical characteristics of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS) cohort: a cross-sectional analysis of baseline data. Lancet Neurol. 2015;14(2): 174-82 (Impact(2014)=21.896, Typ=Article; Journal Article; Clinical Trial; Multicenter Study; Research Support, Non-U.S. Gov't)

Hoang-Xuan K, Bessell E, Bromberg J, Hottinger AF, Preusser M, Rudà R, Schlegel U, Siegal T, Soussain C, Abacioglu U, Cassoux N, Deckert M, Dirven CM, Ferreri AJ, Graus F, Henriksson R, Herrlinger U, Taphoorn M, Soffietti R, Weller M, European Association for Neuro-Oncology Task Force on Primary CNS Lymphoma. Diagnosis and treatment of primary CNS lymphoma in immunocompetent patients: guidelines from the European Association for Neuro-Oncology. Lancet Oncol. 2015;16(7): e322-32 (Impact(2014)=24.69, Typ=Review; Journal Article; Review)

Walter J. Twenty Years of Presenilins--Important Proteins in Health and Disease. Mol Med. 2015;21 Suppl 1: S41-8 (Impact(2014)=4.508, Typ=Review; Journal Article; Research Support, Non-U.S. Gov't)

Kummer MP, Schwarzenberger R, Sayah-Jeanne S, Dubernet M, Walczak R, Hum DW, Schwartz S, Axt D, Heneka MT. Pan-PPAR modulation effectively protects APP/PS1 mice from amyloid deposition and cognitive deficits. Mol Neurobiol. 2015;51(2): 661-71 (Impact(2014)=5.137, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Schmitt I, Kaut O, Khazneh H, deBoni L, Ahmad A, Berg D, Klein C, Fröhlich H, Wüllner U. L-dopa increases ?-synuclein DNA methylation in Parkinson's disease patients in vivo and in vitro. Mov Disord. 2015;30(13): 1794-801 (Impact(2014)=5.68, Typ=Article; Journal Article)

van Loo KM, Schaub C, Pitsch J, Kulbida R, Opitz T, Ekstein D, Dalal A, Urbach H, Beck H, Yaari Y, Schoch S, Becker AJ. Zinc regulates a key transcriptional pathway for epileptogenesis via metal-regulatory transcription factor 1. Nat Commun. 2015;6: 8688 (Impact(2014)=11.47, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Heneka MT, Golenbock DT, Latz E. Innate immunity in Alzheimer's disease. Nat Immunol. 2015;16(3): 229-236 (Impact(2014)=20.004, Typ=Review; Review)

Heilmann S, Drichel D, Clarimon J, Fernández V, Lacour A, Wagner H, Thelen M, Hernández I, Fortea J, Alegret M, Blesa R, Mauleón A, Roca MR, Kornhuber J, Peters O, Heun R, Frölich L, Hüll M, Heneka MT, Rüther E, Riedel-Heller S, Scherer M, Wiltfang J, Jessen F, Becker T, Tárraga L, Boada M, Maier W, Lleó A, Ruiz A, Nöthen MM, Ramirez A, Ramirez A. PLD3 in non-familial Alzheimer's disease. Nature. 2015;520(7545): E3-5 (Impact(2014)=41.456, Typ=Letter; Comment; Letter)

Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, Kootar S, Hornburg D, Evans LD, Moore S, Daria A, Hampel H, Müller V, Giudici C, Nuscher B, Wenninger-Weinzierl A, Kremmer E, Heneka MT, Thal DR, Giedraitis V, Lannfelt L, Müller U, Livesey FJ, Meissner F, Herms J, Konnerth A, Marie H, Haass C. ?-Secretase processing of APP inhibits neuronal activity in the hippocampus. Nature. 2015;526(7573): 443-7 (Impact(2014)=41.456, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Herrlinger U, Platten M. [Treatment of the glioma microenvironment]. Nervenarzt. 2015;86(6): 684, 686-8, 690-1 (Impact(2014)=0.787, Typ=Article; Journal Article; Review; English Abstract)

de Boni L, Riedel L, Schmitt I, Kraus TF, Kaut O, Piston D, Akbarian S, Wüllner U. DNA methylation levels of ?-synuclein intron 1 in the aging brain. Neurobiol Aging. 2015;36(12): 3334.e7-11 (Impact(2014)=5.013, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Korfel A, Thiel E, Martus P, Möhle R, Griesinger F, Rauch M, Röth A, Hertenstein B, Fischer T, Hundsberger T, Mergenthaler HG, Junghanß C, Birnbaum T, Fischer L, Jahnke K, Herrlinger U, Roth P, Bamberg M, Pietsch T, Weller M. Randomized phase III study of whole-brain radiotherapy for primary CNS lymphoma. Neurology. 2015;84(12): 1242-8 (Impact(2014)=8.185, Typ=Article; Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial; Research Support, Non-U.S. Gov't)

Maas RP, van Gaalen J, Klockgether T, van de Warrenburg BP. The preclinical stage of spinocerebellar ataxias. Neurology. 2015;85(1): 96-103 (Impact(2014)=8.185, Typ=Review; Journal Article; Review)

Ashby EL, Miners JS, Kumar S, Walter J, Love S, Kehoe PG. Investigation of A? phosphorylated at serine 8 (pA?) in Alzheimer's disease, dementia with Lewy bodies and vascular dementia. Neuropathol Appl Neurobiol. 2015;41(4): 428-44 (Impact(2014)=3.927, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Urbach H, Rauer S, Mader I, Paus S, Wagner J, Malter MP, Prüss H, Lewerenz J, Kassubek J, Hegen H, Auer M, Deisenhammer F, Ufer F, Bien CG, Baumgartner A. Supratentorial white matter blurring associated with voltage-gated potassium channel-complex limbic encephalitis. Neuroradiology. 2015;57(12): 1203-9 (Impact(2014)=2.485, Typ=Article; Journal Article)

Bach JP, Gold M, Mengel D, Hattesohl A, Lubbe D, Schmid S, Tackenberg B, Rieke J, Maddula S, Baumbach JI, Nell C, Boeselt T, Michelis J, Alferink J, Heneka M, Oertel W, Jessen F, Janciauskiene S, Vogelmeier C, Dodel R, Koczulla AR. Measuring Compounds in Exhaled Air to Detect Alzheimer's Disease and Parkinson's Disease. PLoS ONE. 2015;10(7): e0132227 (Impact(2014)=3.234, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't)

Daniels CML, Paffenrothl E, Austin EV, Glebov K, Lewis D, Walter J, Messing A. Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease PLoS ONE. 2015;10(9): e0138132- (Impact(2014)=3.234, Typ=Article)

Ehrentraut H, Felix Ehrentraut S, Boehm O, El Aissati S, Foltz F, Goelz L, Goertz D, Kebir S, Weisheit C, Wolf M, Meyer R, Baumgarten G. Tlr4 Deficiency Protects against Cardiac Pressure Overload Induced Hyperinflammation. PLoS ONE. 2015;10(11): e0142921 (Impact(2014)=3.234, Typ=Article; Journal Article)

Younesi E, Malhotra A, Gündel M, Scordis P, Kodamullil AT, Page M, Müller B, Springstubbe S, Wüllner U, Scheller D, Hofmann-Apitius M. PDON: Parkinson's disease ontology for representation and modeling of the Parkinson's disease knowledge domain. Theor Biol Med Model. 2015;12: 20 (Impact(2014)=0.95, Typ=Article; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural)