Klinik und Poliklinik für Neurologie

Publikationen 2008

Althaus A, Arránz Becker O, Spottke A, Dengler R, Schneider F, Kloss M, Eggert K, Oertel WH, Dillmann U, Herting B, Classen J, Dodel R. Frequency and treatment of depressive symptoms in a Parkinson's disease registry. Parkinsonism Relat Disord. 2008;14(8):626-32.

Bacher M, Dodel R, Aljabari B, Keyvani K, Marambaud P, Kayed R, Glabe C, Goertz N, Hoppmann A, Sachser N, Klotsche J, Schnell S, Lewejohann L, Al-Abed Y. CNI-1493 inhibits Abeta production, plaque formation, and cognitive deterioration in an animal model of Alzheimer's disease. J Exp Med. 2008;205(7):1593-9.

Bernard V, Stricker S, Kreuz F, Minnerop M, Gillessen-Kaesbach G, Zühlke C. Ataxia with oculomotor apraxia type 2: novel mutations in six patients with juvenile age of onset and elevated serum alpha-fetoprotein. Neuropediatrics. 2008;39(6):347-50.

Biskup S, Gerlach M, Kupsch A, Reichmann H, Riederer P, Vieregge P, Wüllner U, Gasser T. Genes associated with Parkinson syndrome. J Neurol. 2008;255 Suppl:8-17.

Boes M, Pels H, Klockgether T, Koch A, Schlegel U. High-grade B-cell NHL of the brachial plexus followed by infiltration of the spinal cord. J Neurol. 2008;255(1):135-7.

Claeys KG, Fardeau M, Schröder R, Suominen T, Tolksdorf K, Behin A, Dubourg O, Eymard B, Maisonobe T, Stojkovic T, Faulkner G, Richard P, Vicart P, Udd B, Voit T, Stoltenburg G. Electron microscopy in myofibrillar myopathies reveals clues to the mutated gene. Neuromuscul Disord. 2008;18(8):656-66.

Fischer D, Kley RA, Strach K, Meyer C, Sommer T, Eger K, Rolfs A, Meyer W, Pou A, Pradas J, Heyer CM, Grossmann A, Huebner A, Kress W, Reimann J, Schröder R, Eymard B, Fardeau M, Udd B, Goldfarb L, Vorgerd M, Olivé M. Distinct muscle imaging patterns in myofibrillar myopathies. Neurology. 2008;71(10):758-65.

Gilman S, Wenning GK, Low PA, Brooks DJ, Mathias CJ, Trojanowski JQ, Wood NW, Colosimo C, Dürr A, Fowler CJ, Kaufmann H, Klockgether T, Lees A, Poewe W, Quinn N, Revesz T, Robertson D, Sandroni P, Seppi K, Vidailhet M. Second consensus statement on the diagnosis of multiple system atrophy. Neurology. 2008;71(9):670-6.

Glas M, Hennemann B, Hirschmann B, Marienhagen J, Schmidt-Wolf I, Herrlinger U, Bogdahn U, Hau P. Complete response after treatment with a somatostatin analogue in an adult patient with recurrent medulloblastoma. Acta Oncol. 2008;47(3):479-80.

Glas M, Rasch K, Wiewrodt D, Weller M, Herrlinger U. Procarbazine and CCNU as initial treatment in gliomatosis cerebri. Oncology. 2008;75(3-4):182-5.

Glas M, Stuplich M, Tschampa H, Urbach H, Rasch K, Herrlinger U. Liposomal cytarabine given concomitantly with radiotherapy in a patient with leptomeningeal metastasis from breast cancer. J Neurol. 2008;255(11):1838-9.

Globas C, du Montcel ST, Baliko L, Boesch S, Depondt C, DiDonato S, Durr A, Filla A, Klockgether T, Mariotti C, Melegh B, Rakowicz M, Ribai P, Rola R, Schmitz-Hübsch T, Szymanski S, Timmann D, Van de Warrenburg BP, Bauer P, Schols L. Early symptoms in spinocerebellar ataxia type 1, 2, 3, and 6. Mov Disord. 2008;23(15):2232-8.

Herrlinger U, Astner S, Thiel E. Neoplastic meningeosis as connection with CNS involvement by solid tumors. Consequences for diagnosis and treatment. Onkologe. 2008;14(3):267-73.

Hillemacher T, Frieling H, Moskau S, Muschler MA, Semmler A, Kornhuber J, Klockgether T, Bleich S, Linnebank M. Global DNA methylation is influenced by smoking behaviour. Eur Neuropsychopharmacol. 2008;18(4):295-8.

Hofer MJ, Carter SL, Müller M, Campbell IL. Unaltered neurological disease and mortality in CXCR3-deficient mice infected intracranially with lymphocytic choriomeningitis virus-Armstrong. Viral Immunol. 2008;21(4):425-33.

Jeub M, Bitoun M, Guicheney P, Kappes-Horn K, Strach K, Druschky KF, Weis J, Fischer D. Dynamin 2-related centronuclear myopathy: clinical, histological and genetic aspects of further patients and review of the literature. Clin Neuropathol. 2008;27(6):430-8.

Kaut O, Klockgether T. 51-year-old female with steroid-responsive optic neuropathy: a new case of chronic relapsing inflammatory optic neuropathy (CRION). J Neurol. 2008;255(9):1419-20.

Kaut O, Urbach H, Klockgether T. Improvement of paraplegia caused by spinal dural arteriovenous fistula by surgical obliteration more than 6 years after symptom onset. J Neurol Neurosurg Psychiatry. 2008;79(12):1408-9.

Klockgether T. The clinical diagnosis of autosomal dominant spinocerebellar ataxias. Cerebellum. 2008;7(2):101-5.

Köllensperger M, Geser F, Seppi K, Stampfer-Kountchev M, Sawires M, Scherfler C, Boesch S, Mueller J, Koukouni V, Quinn N, Pellecchia MT, Barone P, Schimke N, Dodel R, Oertel W, Dupont E, Østergaard K, Daniels C, Deuschl G, Gurevich T, Giladi N, Coelho M, Sampaio C, Nilsson C, Widner H, Sorbo FD, Albanese A, Cardozo A, Tolosa E, Abele M, Klockgether T, Kamm C, Gasser T, Djaldetti R, Colosimo C, Meco G, Schrag A, Poewe W, Wenning GK, European MSA Study Group. Red flags for multiple system atrophy. Mov Disord. 2008;23(8):1093-9.

Kornblum C, Zsurka G, Wiesner RJ, Schröder R, Kunz WS. Concerted action of two novel tRNA mtDNA point mutations in chronic progressive external ophthalmoplegia. Biosci Rep. 2008;28(2):89-96.

Küker W, Gaertner S, Nagele T, Dopfer C, Schoning M, Fiehler J, Rothwell PM, Herrlinger U. Vessel wall contrast enhancement: a diagnostic sign of cerebral vasculitis. Cerebrovasc Dis. 2008;26(1):23-9.

Kummer MP, Heneka MT. PPARs in Alzheimer's Disease. PPAR Res. 2008;2008:403896.

Kurzwelly D, Müller CA, Korfel A, Thiel E, Linnebank M, Weller M, Herrlinger U. Primary CNS lymphoma and HLA class I and II alleles in a German cohort of immunocompetent patients. J Neurooncol. 2008;90(1):53-5.

Linnebank M, Semmler A, Moskau S, Smulders Y, Blom H, Simon M. The methylenetetrahydrofolate reductase (MTHFR) variant c.677C>T (A222V) influences overall survival of patients with glioblastoma multiforme. Neuro-oncol. 2008;10(4):548-52.

Minnerop M, Herbst M, Fimmers R, Matz B, Klockgether T, Wüllner U. Bell's palsy: Combined treatment of famciclovir and prednisone is superior to prednisone alone. J Neurol. 2008;255(11):1726-30.

Minnerop M, Lüders E, Specht K, Ruhlmann J, Schneider-Gold C, Schröder R, Thompson PM, Toga AW, Klockgether T, Kornblum C. Grey and white matter loss along cerebral midline structures in myotonic dystrophy type 2. J Neurol. 2008;255(12):1904-9.

Müller MC, Jüptner U, Wüllner U, Wirz S, Türler A, Wirtz DC, Hirner A, Standop J. [Parkinson's disease influences the perioperative risk profile in trauma patients]. Z Orthop Unfall. 2008;146(2):227-30.

Nelles M, Block W, Träber F, Wüllner U, Schild HH, Urbach H. Combined 3T diffusion tensor tractography and 1H-MR spectroscopy in motor neuron disease. AJNR Am J Neuroradiol. 2008;29(9):1708-14.

Nelles M, Gieseke J, Flacke S, Lachenmayer L, Schild HH, Urbach H. Diffusion tensor pyramidal tractography in patients with anterior choroidal artery infarcts. AJNR Am J Neuroradiol. 2008;29(3):488-93.

Nuber S, Petrasch-Parwez E, Winner B, Winkler J, von Hörsten S, Schmidt T, Boy J, Kuhn M, Nguyen HP, Teismann P, Schulz JB, Neumann M, Pichler BJ, Reischl G, Holzmann C, Schmitt I, Bornemann A, Kuhn W, Zimmermann F, Servadio A, Riess O. Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease. J Neurosci. 2008;28(10):2471-84.

Paus S, Grünewald A, Klein C, Knapp M, Zimprich A, Janetzky B, Möller JC, Klockgether T, Wüllner U. The DRD2 TaqIA polymorphism and demand of dopaminergic medication in Parkinson's disease. Mov Disord. 2008;23(4):599-602.

Paus S, Zsurka G, Baron M, Deschauer M, Bamberg C, Klockgether T, Kunz WS, Kornblum C. Apraxia of lid opening mimicking ptosis in compound heterozygosity for A467T and W748S POLG1 mutations. Mov Disord. 2008;23(9):1286-8.

Pieper HC, Evert BO, Kaut O, Riederer PF, Waha A, Wüllner U. Different methylation of the TNF-alpha promoter in cortex and substantia nigra: Implications for selective neuronal vulnerability. Neurobiol Dis. 2008;32(3):521-7.

Riedel O, Klotsche J, Spottke A, Deuschl G, Förstl H, Henn F, Heuser I, Oertel W, Reichmann H, Riederer P, Trenkwalder C, Dodel R, Wittchen HU. Cognitive impairment in 873 patients with idiopathic Parkinson's disease. Results from the German Study on Epidemiology of Parkinson's Disease with Dementia (GEPAD). J Neurol. 2008;255(2):255-64.

Sastre M, Walter J, Gentleman SM. Interactions between APP secretases and inflammatory mediators. J Neuroinflammation. 2008;5:25.

Schmitz-Hübsch T, Coudert M, Bauer P, Giunti P, Globas C, Baliko L, Filla A, Mariotti C, Rakowicz M, Charles P, Ribai P, Szymanski S, Infante J, van de Warrenburg BP, Dürr A, Timmann D, Boesch S, Fancellu R, Rola R, Depondt C, Schöls L, Zdienicka E, Kang JS, Döhlinger S, Kremer B, Stephenson DA, Melegh B, Pandolfo M, di Donato S, du Montcel ST, Klockgether T. Spinocerebellar ataxia types 1, 2, 3, and 6: disease severity and nonataxia symptoms. Neurology. 2008;71(13):982-9.

Schmitz-Hübsch T, Giunti P, Stephenson DA, Globas C, Baliko L, Saccà F, Mariotti C, Rakowicz M, Szymanski S, Infante J, van de Warrenburg BP, Timmann D, Fancellu R, Rola R, Depondt C, Schöls L, Zdzienicka E, Kang JS, Döhlinger S, Kremer B, Melegh B, Filla A, Klockgether T. SCA Functional Index: a useful compound performance measure for spinocerebellar ataxia. Neurology. 2008;71(7):486-92.

Schmitz-Hübsch T, Klockgether T. An update on inherited ataxias. Curr Neurol Neurosci Rep. 2008;8(4):310-9.

Semmler A, Hermann S, Mormann F, Weberpals M, Paxian SA, Okulla T, Schäfers M, Kummer MP, Klockgether T, Heneka MT. Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism. J Neuroinflammation. 2008;5:38.

Semmler A, Linnebank M, Krex D, Götz A, Moskau S, Ziegler A, Simon M. Polymorphisms of homocysteine metabolism are associated with intracranial aneurysms. Cerebrovasc Dis. 2008;26(4):425-9.

Semmler A, Simon M, Moskau S, Linnebank M. Polymorphisms of methionine metabolism and susceptibility to meningioma formation: laboratory investigation. J Neurosurg. 2008;108(5):999-1004.

Semmler A, Smulders Y, Struys E, Smith D, Moskau S, Blom H, Linnebank M. Methionine metabolism in an animal model of sepsis. Clin Chem Lab Med. 2008;46(10):1398-402.

Semmler A, von Falkenhausen M, Schröder R. Suprascapular nerve entrapment by a spinoglenoid cyst. Neurology. 2008;70(11):890.

Seufert S, Coras R, Tränkle C, Zlotos DP, Blümcke I, Tatenhorst L, Heneka MT, Hahnen E. PPAR Gamma Activators: Off-Target Against Glioma Cell Migration and Brain Invasion. PPAR Res. 2008;2008:513943.

Standop J, Juptner U, Müller MC, Overhaus M, Wirz S, Hirner A, Wüllner U. Postoperative Complications in Patients with Parkinson's Disease - Medical and Economic Aspects. Akt Neurol. 2008;35(6):285-9.

Strach K, Sommer T, Grohé C, Meyer C, Fischer D, Walter MC, Vorgerd M, Reilich P, Bär H, Reimann J, Reuner U, Germing A, Goebel HH, Lochmüller H, Wintersperger B, Schröder R. Clinical, genetic, and cardiac magnetic resonance imaging findings in primary desminopathies. Neuromuscul Disord. 2008;18(6):475-82.

Tamboli IY, Prager K, Thal DR, Thelen KM, Dewachter I, Pietrzik CU, St George-Hyslop P, Sisodia SS, De Strooper B, Heneka MT, Filippov MA, Müller U, van Leuven F, Lütjohann D, Walter J. Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis. J Neurosci. 2008;28(46):12097-106.

Tatenhorst L, Hahnen E, Heneka MT. Peroxisome Proliferator-Activated Receptors (PPARs) as Potential Inducers of Antineoplastic Effects in CNS Tumors. PPAR Res. 2008;2008:204514.

Utter S, Tamboli IY, Walter J, Upadhaya AR, Birkenmeier G, Pietrzik CU, Ghebremedhin E, Thal DR. Cerebral small vessel disease-induced apolipoprotein E leakage is associated with Alzheimer disease and the accumulation of amyloid beta-protein in perivascular astrocytes. J Neuropathol Exp Neurol. 2008;67(9):842-56.

van den Elskamp IJ, Lembcke J, Dattola V, Beckmann K, Pohl C, Hong W, Sandbrink R, Wagner K, Knol DL, Uitdehaag B, Barkhof F. Persistent T1 hypointensity as an MRI marker for treatment efficacy in multiple sclerosis. Mult Scler. 2008;14(6):764-9.

Wabbels B, Ali N, Kunz WS, Roggenkämper P, Kornblum C. [Chronic progressive external ophthalmoplegia and Kearns-Sayre syndrome: interdisciplinary diagnosis and therapy]. Ophthalmologe. 2008;105(6):550-6.

Waerzeggers Y, Klein M, Miletic H, Himmelreich U, Li H, Monfared P, Herrlinger U, Hoehn M, Coenen HH, Weller M, Winkeler A, Jacobs AH. Multimodal imaging of neural progenitor cell fate in rodents. Mol Imaging. 2008;7(2):77-91.

Wattjes MP, Harzheim M, Lutterbey GG, Bogdanow M, Schild HH, Träber F. High field MR imaging and 1H-MR spectroscopy in clinically isolated syndromes suggestive of multiple sclerosis: correlation between metabolic alterations and diagnostic MR imaging criteria. J Neurol. 2008;255(1):56-63.

Wattjes MP, Harzheim M, Lutterbey GG, Bogdanow M, Schmidt S, Schild HH, Träber F. Prognostic value of high-field proton magnetic resonance spectroscopy in patients presenting with clinically isolated syndromes suggestive of multiple sclerosis. Neuroradiology. 2008;50(2):123-9.

Wattjes MP, Harzheim M, Lutterbey GG, Hojati F, Simon B, Schmidt S, Schild HH, Barkhof F. Does high field MRI allow an earlier diagnosis of multiple sclerosis? J Neurol. 2008;255(8):1159-63.

Wüllner U, Gündisch D, Herzog H, Minnerop M, Joe A, Warnecke M, Jessen F, Schütz C, Reinhardt M, Eschner W, Klockgether T, Schmaljohann J. Smoking upregulates alpha4beta2nicotinic acetylcholine receptors in the human brain. Neurosci Lett. 2008;430(1):34-7.

Zsurka G, Baron M, Stewart JD, Kornblum C, Bös M, Sassen R, Taylor RW, Elger CE, Chinnery PF, Kunz WS. Clonally expanded mitochondrial DNA mutations in epileptic individuals with mutated DNA polymerase gamma. J Neuropathol Exp Neurol. 2008;67(9):857-66.