Klinik und Poliklinik für Neurologie

Publikationen 2003

Abele M, Riet A, Hummel T, Klockgether T, Wüllner U. Olfactory dysfunction in cerebellar ataxia and multiple system atrophy. J Neurol. 2003;250:1453-5.

Abele M, Schöls L, Schwartz S, Klockgether T. Prevalence of antigliadin antibodies in ataxia patients. Neurology. 2003;60:1674-5.

Albrecht M, Hoffmann D, Evert BO, Schmitt I, Wüllner U, Lengauer T. Structural modeling of ataxin-3 reveals distant homology to adaptins. Proteins. 2003;50:355-70.

Bönnemann CG, Thompson TG, van der Ven PF, Goebel HH, Warlo I, Vollmers B, Reimann J, Herms J, Gautel M, Takada F, Beggs AH, Fürst DO, Kunkel LM, Hanefeld F, Schröder R. Filamin C accumulation is a strong but nonspecific immunohistochemical marker of core formation in muscle. J Neurol Sci. 2003;206:71-8.

Bosbach S, Kornblum C, Schröder R, Wagner M. Executive and visuospatial deficits in patients with chronic progressive external ophthalmoplegia and Kearns-Sayre syndrome. Brain. 2003;126:1231-40.

Bürk K, Globas C, Bösch S, Klockgether T, Zühlke C, Daum I, Dichgans J. Cognitive deficits in spinocerebellar ataxia type 1, 2, and 3. J Neurol. 2003;250:207-11.

Depboylu C, Du Y, Müller U, Kurz A, Zimmer R, Riemenschneider M, Gasser T, Oertel WH, Klockgether T, Dodel RC, Oertelf WH. Lack of association of interleukin-10 promoter region polymorphisms with Alzheimer's disease. Neurosci Lett. 2003;342:132-4.

Dodel R, Walbert T, Siebert U. Decision analysis in health economics and Parkinson's disease. Akt Neurol. 2003;30:S249-59.

Dodel RC, Hampel H, Du Y. Immunotherapy for Alzheimer's disease. Lancet Neurol. 2003;2:215-20.

Dodel RC, Höffken H, Möller JC, Bornschein B, Klockgether T, Behr T, Oertel WH, Siebert U. Dopamine transporter imaging and SPECT in diagnostic work-up of Parkinson's disease: a decision-analytic approach. Mov Disord. 2003;18 Suppl 7:S52-62.

Du Y, Wei X, Dodel R, Sommer N, Hampel H, Gao F, Ma Z, Zhao L, Oertel WH, Farlow M. Human anti-beta-amyloid antibodies block beta-amyloid fibril formation and prevent beta-amyloid-induced neurotoxicity. Brain. 2003;126:1935-9.

Evert BO, Vogt IR, Vieira-Saecker AM, Ozimek L, de Vos RA, Brunt ER, Klockgether T, Wüllner U. Gene expression profiling in ataxin-3 expressing cell lines reveals distinct effects of normal and mutant ataxin-3. J Neuropathol Exp Neurol. 2003;62:1006-18.

Fischer D, Aurino S, Nigro V, Schröder R. On symptomatic heterozygous alpha-sarcoglycan gene mutation carriers. Ann Neurol. 2003;54:674-8.

Fischer D, Paus S, Schröder R. [Diagnosis and differential diagnosis of lysosomal glycogen storage disease]. Nervenarzt. 2003;74:896-9.

Fischer D, Reimann J, Schröder R. [Macrophagic myofasciitis: inflammatory, vaccination-associated muscular disease]. Dtsch Med Wochenschr. 2003;128:2305-8.

Fischer D, Schroers A, Blümcke I, Urbach H, Zerres K, Mortier W, Vorgerd M, Schröder R. Consequences of a novel caveolin-3 mutation in a large German family. Ann Neurol. 2003;53:233-41.

Fliessbach K, Urbach H, Helmstaedter C, Pels H, Glasmacher A, Kraus JA, Klockgether T, Schmidt-Wolf I, Schlegel U. Cognitive performance and magnetic resonance imaging findings after high-dose systemic and intraventricular chemotherapy for primary central nervous system lymphoma. Arch Neurol. 2003;60:563-8.

Galea E, Heneka MT, Dello Russo C, Feinstein DL. Intrinsic regulation of brain inflammatory responses. Cell Mol Neurobiol. 2003;23:625-35.

Gasser T, Bressman S, Dürr A, Higgins J, Klockgether T, Myers RH. State of the art review: molecular diagnosis of inherited movement disorders. Movement Disorders Society task force on molecular diagnosis. Mov Disord. 2003;18:3-18.

Harzheim M, Altenschmidt M, Heneka MT, Schröder R, Klockgether T, Schmidt S. IFN-beta1a (Rebif) modifies the expression of microfilament-associated cell-cell contacts in C6 glioma cells. J Interferon Cytokine Res. 2003;23:83-9.

Heneka MT, Gavrilyuk V, Landreth GE, O'Banion MK, Weinberg G, Feinstein DL. Noradrenergic depletion increases inflammatory responses in brain: effects on IkappaB and HSP70 expression. J Neurochem. 2003;85:387-98.

Holzmann C, Krüger R, Saecker AM, Schmitt I, Schöls L, Berger K, Riess O. Polymorphisms of the alpha-synuclein promoter: expression analyses and association studies in Parkinson's disease. J Neural Transm. 2003;110:67-76.

Hundsberger T, Koch D, Klimpe S, Schlegel U. Treatment of malignant gliomas with temozolomide. Akt Neurol. 2003;30:184-7.

Klockgether T. [Medicinal treatment of idiopathic Parkinson's disease]. Nervenarzt. 2003;74 Suppl 1:S12-21.

Klotz L, Sastre M, Kreutz A, Gavrilyuk V, Klockgether T, Feinstein DL, Heneka MT. Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARgamma) in murine primary astrocytes and neurons. J Neurochem. 2003;86:907-16.

Kraner S, Laufenberg I, Strassburg HM, Sieb JP, Steinlein OK. Congenital myasthenic syndrome with episodic apnea in patients homozygous for a CHAT missense mutation. Arch Neurol. 2003;60:761-3.

Lampe JB, Gossrau G, Kempe A, Füssel M, Schwurack K, Schröder R, Krause S, Kohnen R, Walter MC, Reichmann H, Lochmüller H. Analysis of HLA class I and II alleles in sporadic inclusion-body myositis. J Neurol. 2003;250:1313-7.

Lin S, Wei X, Xu Y, Yan C, Dodel R, Zhang Y, Liu J, Klaunig JE, Farlow M, Du Y. Minocycline blocks 6-hydroxydopamine-induced neurotoxicity and free radical production in rat cerebellar granule neurons. Life Sci. 2003;72:1635-41.

Linnebank M, Junker R, Nabavi DG, Linnebank A, Koch HG. Isolated thrombosis due to the cystathionine beta-synthase mutation c. 833T>C (1278T). J Inherit Metab Dis. 2003;26:509-11.

Linnebank M, Kesper K, Jeub M, Urbach H, Wüllner U, Klockgether T, Schmidt S. Hereditary elevation of angiotensin converting enzyme suggesting neurosarcoidosis. Neurology. 2003;61:1819-20.

Minnerop M, Bos M, Harbrecht U, Maass M, Urbach H, Klockgether T, Schroder R. CNS infection with C. pneumoniae complicated by multiple strokes - Reply. J Neurol. 2003;250:1128.

Moskau S, Urbach H, Hartmann A, Schmidt S. Multifocal myelitis in Behçet's disease. Neurology. 2003;60:517.

Oertel WH, Gerstner A, Höffken H, Dodel RC, Eggert KM, Möller JC. Role of dopamine transporter SPECT for the practitioner and the general neurologist. Mov Disord. 2003;18 Suppl 7:S9-15.

Omran H, Schmidt H, Hackenbroch M, Illien S, Bernhardt P, von der Recke G, Fimmers R, Flacke S, Layer G, Pohl C, Lüderitz B, Schild H, Sommer T. Silent and apparent cerebral embolism after retrograde catheterisation of the aortic valve in valvular stenosis: a prospective, randomised study. Lancet. 2003;361:1241-6.

Paus S, Brecht HM, Klockgether T, Wullner U. Reply: Sleep attacks may not be a side effect of dopaminergic medication. Mov Disord. 2003;18:1571.

Paus S, Brecht HM, Köster J, Seeger G, Klockgether T, Wüllner U. Sleep attacks, daytime sleepiness, and dopamine agonists in Parkinson's disease. Mov Disord. 2003;18:659-67.

Paus S, Klockgether T, Urbach H, Schlegel U. Meningioma of the optic nerve sheath: treatment with hydroxyurea. J Neurol Neurosurg Psychiatry. 2003;74:1348-50.

Pedraza CE, Baltrons MA, Heneka MT, García A. Interleukin-1 beta and lipopolysaccharide decrease soluble guanylyl cyclase in brain cells: NO-independent destabilization of protein and NO-dependent decrease of mRNA. J Neuroimmunol. 2003;144:80-90.

Pels H, Schmidt-Wolf IG, Glasmacher A, Schulz H, Engert A, Diehl V, Zellner A, Schackert G, Reichmann H, Kroschinsky F, Vogt-Schaden M, Egerer G, Bode U, Schaller C, Deckert M, Fimmers R, Helmstaedter C, Atasoy A, Klockgether T, Schlegel U. Primary central nervous system lymphoma: results of a pilot and phase II study of systemic and intraventricular chemotherapy with deferred radiotherapy. J Clin Oncol. 2003;21:4489-95.

Pels H, Schulz H, Schlegel U, Engert A. Treatment of CNS lymphoma with the anti-CD20 antibody rituximab: experience with two cases and review of the literature. Onkologie. 2003;26:351-4.

Reimann J, Kunz WS, Vielhaber S, Kappes-Horn K, Schröder R. Mitochondrial dysfunction in myofibrillar myopathy. Neuropathol Appl Neurobiol. 2003;29:45-51.

Salmikangas P, van der Ven PF, Lalowski M, Taivainen A, Zhao F, Suila H, Schröder R, Lappalainen P, Fürst DO, Carpén O. Myotilin, the limb-girdle muscular dystrophy 1A (LGMD1A) protein, cross-links actin filaments and controls sarcomere assembly. Hum Mol Genet. 2003;12:189-203.

Sastre M, Dewachter I, Landreth GE, Willson TM, Klockgether T, van Leuven F, Heneka MT. Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase. J Neurosci. 2003;23:9796-804.

Schlosser T, Pohl C, Kuntz-Hehner S, Omran H, Becher H, Tiemann K. Echoscintigraphy: a new imaging modality for the reduction of color blooming and acoustic shadowing in contrast sonography. Ultrasound Med Biol. 2003;29:985-91.

Schmidt S, Marrosu GM, Kölsch H, Haase CG, Ferenczik S, Sokolowski P, Köhler W, Schmidt M, Papassotiropoulos A, Heun R, Grosse-Wilde H, Klockgether T. Genetic variations and humoral immune responses to myelin oligodendroglia glycoprotein in adult phenotypes of X-linked adrenoleukodystrophy. J Neuroimmunol. 2003;135:148-53.

Schmidt S, Papassotiropoulos A, Sotgiu S, Kölsch H, Arru G, Fois ML, Haase CG, Schmitz S, König N, Harzheim M, Heun R, Klockgether T. Investigation of a genetic variation of a variable number tandem repeat polymorphism of interleukin-6 gene in patients with multiple sclerosis. J Neurol. 2003;250:607-11.

Schmidt-Wolf IG, Rockstroh JK, Schlegel U, Pels H, Mey U, Strehl J, Weiss R, Huhn D. Treatment options of AIDS-related lymphoma. Expert Opin Pharmacother. 2003;4:1331-43.

Schmitt I, Evert BO, Khazneh H, Klockgether T, Wuellner U. The human MJD gene: genomic structure and functional characterization of the promoter region. Gene. 2003;314:81-8.

Schmitz C, Weinreich S, Schneider R, Schneider D, Speth I, Schulze-Rauschenbach C, Pohl C, Welz A. Off-Pump versus on-pump coronary artery bypass: can OPCAB reduce neurologic injury? Heart Surg Forum. 2003;6:127-30.

Schmitz C, Weinreich S, White J, Oengoeren I, Schneider R, Schneider D, Speth I, Pohl C, Welz A. Can particulate extraction from the ascending aorta reduce neurologic injury in cardiac surgery? J Thorac Cardiovasc Surg. 2003;126:1829-38.

Schröder R, Goudeau B, Simon MC, Fischer D, Eggermann T, Clemen CS, Li Z, Reimann J, Xue Z, Rudnik-Schöneborn S, Zerres K, van der Ven PF, Fürst DO, Kunz WS, Vicart P. On noxious desmin: functional effects of a novel heterozygous desmin insertion mutation on the extrasarcomeric desmin cytoskeleton and mitochondria. Hum Mol Genet. 2003;12:657-69.

Schröder R, Reimann J, Salmikangas P, Clemen CS, Hayashi YK, Nonaka I, Arahata K, Carpén O. Beyond LGMD1A: myotilin is a component of central core lesions and nemaline rods. Neuromuscul Disord. 2003;13:451-5.

Seyfried J, Evert BO, Schwarz CS, Schaupp M, Schulz JB, Klockgether T, Wüllner U. Gene dosage-dependent effects of bcl-2 expression on cellular survival and redox status. Free Radic Biol Med. 2003;34:1517-30.

Sieb JP, Kraner S, Thompson PN, Steinlein OK. Congenital myasthenic syndrome in cattle due to homozygosity for a truncating mutation in the acetylcholine receptor (AChR) epsilon-subunit gene. Ann N Y Acad Sci. 2003;998:125-7.

Smala AM, Spottke EA, Machat O, Siebert U, Meyer D, Köhne-Volland R, Reuther M, DuChane J, Oertel WH, Berger KB, Dodel RC. Cabergoline versus levodopa monotherapy: a decision analysis. Mov Disord. 2003;18:898-905.

Specht K, Minnerop M, Abele M, Reul J, Wüllner U, Klockgether T. In vivo voxel-based morphometry in multiple system atrophy of the cerebellar type. Arch Neurol. 2003;60:1431-5.

Srinivasan J, Suresh B, Ramanathan M. Differential anxiolytic effect of enalapril and losartan in normotensive and renal hypertensive rats. Physiol Behav. 2003;78:585-91.

Thompson PN, Steinlein OK, Harper CK, Kraner S, Sieb JP, Guthrie AJ. Congenital myasthenic syndrome of Brahman cattle in South Africa. Vet Rec. 2003;153:779-81.

Tschampa HJ, Mürtz P, Flacke S, Paus S, Schild HH, Urbach H. Thalamic involvement in sporadic Creutzfeldt-Jakob disease: a diffusion-weighted MR imaging study. AJNR Am J Neuroradiol. 2003;24:908-15.

Vielhaber S, Kudin A, Winkler K, Wiedemann F, Schröder R, Feistner H, Heinze HJ, Elger CE, Kunz WS. Is there mitochondrial dysfunction in amyotrophic lateral sclerosis skeletal muscle? Ann Neurol. 2003;53:686-7, author reply 687-8.

Wüllner U. Genes implicated in the pathogenesis of spinocerebellar ataxias. Drugs Today (Barc). 2003;39:927-37.

Zange J, Grehl T, Disselhorst-Klug C, Rau G, Müller K, Schröder R, Tegenthoff M, Malin JP, Vorgerd M. Breakdown of adenine nucleotide pool in fatiguing skeletal muscle in McArdle's disease: a noninvasive 31P-MRS and EMG study. Muscle Nerve. 2003;27:728-36.