Klinik und Poliklinik für Neurologie

Publikationen 2002

Abele M, Bürk K, Schöls L, Schwartz S, Besenthal I, Dichgans J, Zühlke C, Riess O, Klockgether T. The aetiology of sporadic adult-onset ataxia. Brain. 2002;125(Pt 5):961-8.

Baltrons MA, Pedraza CE, Heneka MT, García A. Beta-amyloid peptides decrease soluble guanylyl cyclase expression in astroglial cells. Neurobiol Dis. 2002;10(2):139-49.

Becker AJ, Chen J, Paus S, Normann S, Beck H, Elger CE, Wiestler OD, Blümcke I. Transcriptional profiling in human epilepsy: expression array and single cell real-time qRT-PCR analysis reveal distinct cellular gene regulation. Neuroreport. 2002;13(10):1327-33.

Block W, Träber F, Flacke S, Jessen F, Pohl C, Schild H. In-vivo proton MR-spectroscopy of the human brain: assessment of N-acetylaspartate (NAA) reduction as a marker for neurodegeneration. Amino Acids. 2002;23(1-3):317-23.

Boullerne AI, Rodriguez JJ, Touil T, Brochet B, Schmidt S, Abrous ND, Le Moal M, Pua JR, Jensen MA, Mayo W, Arnason BG, Petry KG. Anti-S-nitrosocysteine antibodies are a predictive marker for demyelination in experimental autoimmune encephalomyelitis: implications for multiple sclerosis. J Neurosci. 2002;22(1):123-32.

Breidert T, Callebert J, Heneka MT, Landreth G, Launay JM, Hirsch EC. Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease. J Neurochem. 2002;82(3):615-24.

Capell A, Meyn L, Fluhrer R, Teplow DB, Walter J, Haass C. Apical sorting of beta-secretase limits amyloid beta-peptide production. J Biol Chem. 2002;277(7):5637-43.

Deschauer M, Wieser T, Schröder R, Zierz S. A novel nonsense mutation (515del4) in muscle carnitine palmitoyltransferase II deficiency. Mol Genet Metab. 2002;75(2):181-5.

Dihné M, Grommes C, Lutzenburg M, Witte OW, Block F. Different mechanisms of secondary neuronal damage in thalamic nuclei after focal cerebral ischemia in rats. Stroke. 2002;33(12):3006-11.

Dodel RC, Du Y, Depboylu C, Kurz A, Eastwood B, Farlow M, Oertel WH, Müller U, Riemenschneider M. A polymorphism in the cystatin C promoter region is not associated with an increased risk of AD. Neurology. 2002;58:664.

Dodel R, Hampel H, Depboylu C, Lin S, Gao F, Schock S, Jackel S, Wei X, Buerger K, Hoft C, Hemmer B, Moller HJ, Farlow M, Oertel WH, Sommer N, Du Y. Human antibodies against amyloid beta peptide: a potential treatment for Alzheimer's disease. Ann Neurol. 2002;52:253-6.

Feinstein DL, Galea E, Gavrilyuk V, Brosnan CF, Whitacre CC, Dumitrescu-Ozimek L, Landreth GE, Pershadsingh HA, Weinberg G, Heneka MT. Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis. Ann Neurol. 2002;51(6):694-702.

Feinstein DL, Heneka MT, Gavrilyuk V, Dello Russo C, Weinberg G, Galea E. Noradrenergic regulation of inflammatory gene expression in brain. Neurochem Int. 2002;41(5):357-65.

Fischer D, Brunn A, Schröder JM, Reul J, Schröder R. Spinal schwannoma mimicking lower limb SMA. Neurology. 2002;59(9):1420.

Fischer D, Matten J, Reimann J, Bönnemann C, Schröder R. Expression, localization and functional divergence of alphaB-crystallin and heat shock protein 27 in core myopathies and neurogenic atrophy. Acta Neuropathol (Berl). 2002;104(3):297-304.

Fischer D, Reimann J, Schröder R, Schmidt S. [Multifocal motor neuropathy: diagnosis and differential diagnosis]. Nervenarzt. 2002;73(12):1153-9.

Fischer D, Schröder R. Granulomatous myositis associated with antithyroglobulin and antithyroid peroxidase antibodies: an analogy to Hashimoto's encephalitis? J Neurol. 2002;249(10):1453-4.

Flacke S, Urbach H, Block W, Träber F, Mürtz P, Keller E, Hartmann A, Schild HH. Perfusion and molecular diffusion-weighted MR imaging of the brain: in vivo assessment of tissue alteration in cerebral ischemia. Amino Acids. 2002;23(1-3):309-16.

Fluhrer R, Capell A, Westmeyer G, Willem M, Hartung B, Condron MM, Teplow DB, Haass C, Walter J. A non-amyloidogenic function of BACE-2 in the secretory pathway. J Neurochem. 2002;81(5):1011-20.

Gao F, Bales KR, Dodel RC, Liu J, Chen X, Hample H, Farlow MR, Paul SM, Du Y. NF-kappaB mediates IL-1beta-induced synthesis/release of alpha2- macroglobulin in a human glial cell line. Brain Res Mol Brain Res. 2002;105:108-14.

Gavrilyuk V, Dello Russo C, Heneka MT, Pelligrino D, Weinberg G, Feinstein DL. Norepinephrine increases I kappa B alpha expression in astrocytes. J Biol Chem. 2002;277(33):29662-8.

Gleichmann M, Buchheim G, El Bizri H, Yokota Y, Klockgether T, Kügler S, Bähr M, Weller M, Schulz JB. Identification of inhibitor-of-differentiation 2 (Id2) as a modulator of neuronal apoptosis. J Neurochem. 2002;80:755-62.

Haase CG, Schmidt S, Faustmann PM. Frequencies of the G-protein beta3 subunit C825T polymorphism and the delta 32 mutation of the chemokine receptor-5 in patients with multiple sclerosis. Neurosci Lett. 2002;330(3):293-5.

Heneka MT, Galea E, Gavriluyk V, Dumitrescu-Ozimek L, Daeschner J, O'Banion MK, Weinberg G, Klockgether T, Feinstein DL. Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: implications for Alzheimer's disease. J Neurosci. 2002;22(7):2434-42.

Kraner S, Burgunder JM, Rösler KM, Steinlein OK, Sieb JP. Congenital myasthenic syndrome due to heteroallelic nonsense/missense mutations in the acetylcholine receptor epsilon subunit gene. Eur J Neurol. 2002;9(6):694-5.

Kraner S, Sieb JP, Thompson PN, Steinlein OK. Congenital myasthenia in Brahman calves caused by homozygosity for a CHRNE truncating mutation. Neurogenetics. 2002;4(2):87-91.

Kraus JA, Felsberg J, Tonn JC, Reifenberger G, Pietsch T. Molecular genetic analysis of the TP53, PTEN, CDKN2A, EGFR, CDK4 and MDM2 tumour-associated genes in supratentorial primitive neuroectodermal tumours and glioblastomas of childhood. Neuropathol Appl Neurobiol. 2002;28(4):325-33.

Kraus JA, Oster C, Sörensen N, Berthold F, Schlegel U, Tonn JC, Wiestler OD, Pietsch T. Human medulloblastomas lack point mutations and homozygous deletions of the hSNF5/INI1 tumour suppressor gene. Neuropathol Appl Neurobiol. 2002;28(2):136-41.

Kraus JA, Stüper BK, Müller J, Nahser HC, Klockgether T, Berlit P, Harbrecht U. Molecular analysis of thrombophilic risk factors in patients with dural arteriovenous fistulas. J Neurol. 2002;249(6):680-2.

Kristof RA, Neuloh G, Hans V, Deckert M, Urbach H, Schlegel U, Simon M, Schramm J. Combined surgery, radiation, and PCV chemotherapy for astrocytomas compared to oligodendrogliomas and oligoastrocytomas WHO grade III. J Neurooncol. 2002;59(3):231-7.

Kudin AP, Kudina TA, Seyfried J, Vielhaber S, Beck H, Elger CE, Kunz WS. Seizure-dependent modulation of mitochondrial oxidative phosphorylation in rat hippocampus. Eur J Neurosci. 2002;15(7):1105-14.

Lammich S, Okochi M, Takeda M, Kaether C, Capell A, Zimmer AK, Edbauer D, Walter J, Steiner H, Haass C. Presenilin dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Abeta-like peptide. J Biol Chem. 2002;277:44754-9.

Minnerop M, Bös M, Harbrecht U, Maass M, Urbach H, Klockgether T, Schröder R. CNS infection with Chlamydia pneumoniae complicated by multiple strokes. J Neurol. 2002;249:1329-31.

Nessler S, Dodel R, Bittner A, Reuss S, Du Y, Hemmer B, Sommer N. Effect of minocycline in experimental autoimmune encephalomyelitis. Ann Neurol. 2002;52:689-90.

Okulla T, Gass S, Böhme K, Tiemann K, Harbrecht U, Klockgether T, Pohl C. Circulating adhesion molecules in patients with internal carotid artery stenosis. Cerebrovasc Dis. 2002;14(1):9-14.

Pels H, Schulz H, Manzke O, Hom E, Thall A, Engert A. Intraventricular and intravenous treatment of a patient with refractory primary CNS lymphoma using rituximab. J Neurooncol. 2002;59:213-6.

Pohl C, Happe J, Klockgether T. Cooling improves the writing performance of patients with writer's cramp. Mov Disord. 2002;17(6):1341-4.

Przuntek H, Bittkau S, Bliesath H, Büttner U, Fuchs G, Glass J, Haller H, Klockgether T, Kraus P, Lachenmayer L, Müller D, Müller T, Rathay B, Sgonina J, Steinijans V, Teshmar E, Ulm G, Volc D. Budipine provides additional benefit in patients with Parkinson disease receiving a stable optimum dopaminergic drug regimen. Arch Neurol. 2002;59(5):803-6.

Schlegel U. Cerebral lymphomas. Akt Neurol. 2002;29(9):460-2.

Schmidt S, Balzer S, Nüllen C, Schmidt M, Pohl C, von Rücker A, Klockgether T. Immunomodulatory effects of glatiramer acetate on superantigen- and mitogen-induced T-cell stimulation in vitro. Mult Scler. 2002;8(4):307-9.

Schmidt-Wolf IG, Rockstroh JK, Schlegel U, Pels H, Weiss R, Huhn D. New aspects in the treatment of AIDS-related lymphoma. Eur J Med Res. 2002;7(7):295-303.

Schröder R, Kunz WS, Rouan F, Pfendner E, Tolksdorf K, Kappes-Horn K, Altenschmidt-Mehring M, Knoblich R, van der Ven PF, Reimann J, Fürst DO, Blümcke I, Vielhaber S, Zillikens D, Eming S, Klockgether T, Uitto J, Wiche G, Rolfs A. Disorganization of the desmin cytoskeleton and mitochondrial dysfunction in plectin-related epidermolysis bullosa simplex with muscular dystrophy. J Neuropathol Exp Neurol. 2002;61(6):520-30.

Schröder R, Pacholsky D, Reimann J, Matten J, Wiche G, Fürst DO, van der Ven PF. Primary longitudinal adhesion structures: plectin-containing precursors of costameres in differentiating human skeletal muscle cells. Histochem Cell Biol. 2002;118(4):301-10.

Schwarz CS, Seyfried J, Evert BO, Klockgether T, Wüllner U. Bcl-2 up-regulates ha-ras mRNA expression and induces c-Jun phosphorylation at Ser73 via an ERK-dependent pathway in PC 12 cells. Neuroreport. 2002;13(18):2439-42.

Semmler A, Urbach H, Klockgether T. Giant cell arteritis causing multiple vertebro-basilar infarcts. Neurology. 2002;58:1399.

Sewry CA, Müller C, Davis M, Dwyer JS, Dove J, Evans G, Schröder R, Fürst D, Helliwell T, Laing N, Quinlivan RC. The spectrum of pathology in central core disease. Neuromuscul Disord. 2002;12(10):930-8.

Spottke EA, Volkmann J, Lorenz D, Krack P, Smala AM, Sturm V, Gerstner A, Berger K, Hellwig D, Deuschl G, Freund HJ, Oertel WH, Dodel RC. Evaluation of healthcare utilization and health status of patients with Parkinson's disease treated with deep brain stimulation of the subthalamic nucleus. J Neurol. 2002;249:759-66.

Urbach H, Hartmann A, Pohl C, Omran H, Wilhelm K, Flacke S, Schild HH, Klockgether T. Local intra-arterial thrombolysis in the carotid territory: does recanalization depend on the thromboembolus type? Neuroradiology. 2002;44(8):695-9.

Varlamov DA, Kudin AP, Vielhaber S, Schröder R, Sassen R, Becker A, Kunz D, Haug K, Rebstock J, Heils A, Elger CE, Kunz WS. Metabolic consequences of a novel missense mutation of the mtDNA CO I gene. Hum Mol Genet. 2002;11(16):1797-805.

Veltmann C, Lohmaier S, Schlosser T, Shai S, Ehlgen A, Pohl C, Becher H, Tiemann K. On the design of a capillary flow phantom for the evaluation of ultrasound contrast agents at very low flow velocities. Ultrasound Med Biol. 2002;28(5):625-34.

Vielhaber S, Varlamov DA, Kudina TA, Schröder R, Kappes-Horn K, Elger CE, Seibel M, Seibel P, Kunz WS. Expression pattern of mitochondrial respiratory chain enzymes in skeletal muscle of patients harboring the A3243G point mutation or large-scale deletions of mitochondrial DNA. J Neuropathol Exp Neurol. 2002;61(10):885-95.

von Schweinitz D, Kraus JA, Albrecht S, Koch A, Fuchs J, Pietsch T. Prognostic impact of molecular genetic alterations in hepatoblastoma. Med Pediatr Oncol. 2002;38(2):104-8.

Vorgerd M, Zange J, Kley R, Grehl T, Hüsing A, Jäger M, Müller K, Schröder R, Mortier W, Fabian K, Malin JP, Luttmann A. Effect of high-dose creatine therapy on symptoms of exercise intolerance in McArdle disease: double-blind, placebo-controlled crossover study. Arch Neurol. 2002;59(1):97-101.

Walter J, Haass C. Secretases as targets for beta-amyloid lowering drugs. Drug Dev Res. 2002;56(2):201-10.

Wick W, Stock J, Seyfried J, Baumgart J, Wüllner U, Weller M. CD95/CD95 ligand-independent potentiation of treosulfan cytotoxicity by BSO in malignant glioma cells in vitro and in vivo. Int J Oncol. 2002;21(1):213-20.

Zander T, Kraus JA, Grommes C, Schlegel U, Feinstein D, Klockgether T, Landreth G, Koenigsknecht J, Heneka MT. Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPARgamma. J Neurochem. 2002;81(5):1052-60.

Zander T, Nettekoven W, Kraus JA, Pels H, Ko YD, Vetter H, Klockgether T, Schlegel U. Intensified PCV-chemotherapy with optional stem cell support in recurrent malignant oligodendroglioma. J Neurol. 2002;249(8):1055-7.

Zange J, Kornblum C, Müller K, Kurtscheid S, Heck H, Schröder R, Grehl T, Vorgerd M. Creatine supplementation results in elevated phosphocreatine/adenosine triphosphate (ATP) ratios in the calf muscle of athletes but not in patients with myopathies. Ann Neurol. 2002;52(1):126; author reply 126-7.

Ziske CG, Schöttker B, Gorschlüter M, Mey U, Kleinschmidt R, Schlegel U, Sauerbruch T, Schmidt-Wolf IG. Acute transient encephalopathy after paclitaxel infusion: report of three cases. Ann Oncol. 2002;13(4):629-31.