Klinik und Poliklinik für Neurologie

Publikationen 2000

Abele M, Schulz JB, Bürk K, Topka H, Dichgans J, Klockgether T. Nerve conduction studies in multiple system atrophy. Eur Neurol. 2000;43:221-3.

Abele M, Schulz JB, Topka H, Dichgans J, Klockgether T. Evoked potentials in multiple system atrophy. Acta Neurol Scand. 2000;101:111-5.

Babbe H, Roers A, Waisman A, Lassmann H, Goebels N, Hohlfeld R, Friese M, Schröder R, Deckert M, Schmidt S, Ravid R, Rajewsky. Clonal expansion of CD8(+) T cells dominante the T cell infiltrate in active multiple sclerosis lesions shown by micromanipulation and single cell polymerase chain reaction. J Exp Med. 2000;192:393-404.

Braks E, Urbach H, Pels H, Traber F, Block W, Schild HH. Primary central nervous system immunocytoma: MRI and spectroscopy. Neuroradiology. 2000;42:738-41.

Broicher R, Kornblum C, Schröder R, Walther E. Secondary cricopharyngeal achalasia in underlying mitochondrial myopathy. Laryngorhinootologie. 2000;79:190-2.

der Ven PF, Wiesner S, Salmikangas P, Auerbach D, Himmel M, Kempa S, Hayess K, Pacholsky D, Taivainen A, Schröder R, Carpen O, Fürst DO. Indications for a novel muscular dystrophy pathway: gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin. J Cell Biol. 2000;151:235-48.

Eunson LH, Rea R, Zuberi SM, Youroukos S, Panayiotopoulos CP, Liguori R, Avoni P, McWilliam RC, Stephenson JB, Hanna MG, Kullmann DM, Spauschus A. Clinical, genetic, and expression studies of mutations in the potassium channel gene KCNA1 reveal new phenotypic variability. Ann Neurol. 2000;48:647-56.

Evert BO, Wüllner U, Klockgether T. Cell death in polyglutamine diseases. Cell Tissue Res. 2000;301:189-204.

Flacke S, Wüllner U, Keller E, Hamzei F, Urbach H. Reversible changes in echo planar perfusion- and diffusion-weighted MRI in status epilepticus. Neuroradiology. 2000;42:92-5.

Gasser T, Dichgans M, Jurkatt-Rott K, Klockgether T, Klopstock T, Kretzschmar H, Lehmann-Horn F, Reichmann H, Rolfs A, Sander T, Stögbauer F. Molekulare Diagnostik erblicher neurologischer Erkrankungen. Nervenarzt. 2000;71:774-96.

Goebels N, Hofstetter H, Schmidt S, Brunner C, Wekerle H, Hohlfeld R. Repertoire dynamics of autoreactive T cells in multiple sclerosis patients and healthy subjects: epitope spreading versus clonal persistence. Brain. 2000;123:508-18.

Harzheim M, Becher H, Klockgether T. Brain infarct from a paradoxical embolism following a varices operation. Dtsch Med Wochenschr. 2000;125:794-6.

Heneka MT, Dumitrescu L, Löschmann PA, Wüllner U, Klockgether T. Temporal, regional, and cell-specific changes of iNOS expression after intrastriatal microinjection of interferon gamma and bacterial lipopolysaccharide. J Chem Neuroanat. 2000;18:167-79.

Heneka MT, Klockgether T, Feinstein DL. Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo. J Neurosci. 2000;15:6862-7.

Heneka MT, Sharp A, Klockgether T, Gavrilyuk V, Feinstein DL. The heat shock response inhibits NF-kappaB activation, nitric oxide synthase type 2 expression, and macrophage/microglial activation in brain. J Cereb Blood Flow Metab. 2000;20:800-11.

Kampermann J, Herbst M Ullrich S. Effects of adrenaline and tolbutamide on insulin secretion in INS-1 cells under voltage control. Cell Physiol Biochem. 2000;10:81-90.

Klockgether T. Recent advances in degenerative ataxias. Curr Opin Neurol. 2000;13:451-5.

Klockgether T, Wüllner U, Spauschus A, Evert B. The molecular biology of the autosomal-dominant cerebellar ataxias. Mov Disord. 2000;15:604-12.

Kraus JA, Glesmann N, Beck M, Krex D, Klockgether T, Schackert G, Schlegel U. Molecular analysis of the PTEN, TP53 and CDKN2A tumor suppressor genes in long-term survivors of glioblastoma multiforme. J Neurooncol. 2000;48:89-94.

Kraus JA, Stuper BK, Nahser HC, Klockgether T, Berlit P. Significantly increased prevalence of factor V Leiden in patients with dural arteriovenous fistulas. J Neurol. 2000;247:521-3.

Kraus JA, Wenghoefer M, Schmidt MC, von Deimling A, Berweiler U, Roggendorf W, Diete S, Dietzmann K, Muller B, Heuser K, Reifenberger G, Schlegel U. Long-term survival of glioblastoma multiforme: importance of histopathological reevaluation. J Neurol. 2000;247:455-60.

Magin TM, Hesse M, Schröder R. Novel insights into intermediate-filament function from studies of transgenic and knockout mice. Protoplasma. 2000;211:140-50.

Pels H, Deckert-Schlüter M, Glasmacher A, Kleinschmidt R, Oehring R, Fischer HP, Bode U, Schlegel U. Primary central nervous system lymphoma: a clinicopathological study of 28 cases. Hematol Oncol. 2000;18:21-32.

Pels H, Vogt I, Klockgether T, Schlegel U. Primary non-Hodgkin's lymphoma of the spinal cord. Spine. 2000;25:2262-4.

Pohl C, Harbrecht U, Greinacher A, Theuerkauf I, Biniek R, Hanfland P, Klockgether T. Neurologic complications in immune-mediated heparin-induced thrombocytopenia. Neurology. 2000;54:1240-5.

Pohl C, Tiemann K, Schlosser T, Becher H. Stimulated acoustic emission detected by transcranial color doppler ultrasound: a contrast-specific phenomenon useful for the detection of cerebral tissue perfusion. Stroke. 2000;31:1661-6.

Schlegel U. Neue Aspekte der Therapie bei Gehirntumoren. Nervenheilkunde. 2000;19:14-20.

Schlegel U, Schmidt-Wolf IG, Deckert M. Primary CNS lymphoma: clinical presentation, pathological classification, molecular pathogenesis and treatment. J Neurol Sci. 2000;181:1-12.

Schmidt S, Papassotiropoulos A, Bagli M, Harzheim M, Heun R, Klockgether T. No association of serum levels of interleukin-6 and its soluble receptor components with a genetic variation in the 3'flanking region of the interleukin-6 gene in patients with multiple sclerosis. Neurosci Lett. 2000;294:139-42.

Schröder R, Fürst DO, Klasen C, Reimann J, Herrmann H, van der Ven PF. Association of plectin with Z-discs is a prerequisite for the formation of the intermyofibrillar desmin cytoskeleton. Lab Invest. 2000;80:455-64.

Schröder R, van der Ven PF, Warlo I, Schumann H, Fürst DO, Blümcke I, Schmidt MC, Hatzfeld M. p0071, a member of the armadillo multigene family, is a constituent of sarcomeric I-bands in human skeletal muscle. J Muscle Res Cell Motil. 2000;21:577-86.

Schröder R, Vielhaber S, Wiedemann FR, Kornblum C, Papassotiropoulos A, Broich P, Zierz S, Elger CE, Reichmann H, Seibel P, Klockgether T, Kunz WS. New insights into the metabolic consequences of large-scale mtDNA deletions: a quantitative analysis of biochemical, morphological, and genetic findings in human skeletal muscle. J Neuropathol Exp Neurol. 2000;59:353-60.

Schulz JB, Lindenau J, Seyfried J, Dichgans J. Glutathione, oxidative stress and neurodegeneration. Eur J Biochem. 2000;267:4904-11.

Seyfried J, Evert BO, Rundfeldt C, Schulz JB, Kovar KA, Klockgether T, Wüllner U. Flupirtine and retigabine prevent L-glutamate toxicity in rat pheochromocytoma PC12 cells. Eur J Pharmacol. 2000;400:155-66.

Seyfried J, Soldner F, Kunz WS, Schulz JB, Klockgether T, Kovar KA, Wüllner U. Effect of 1-methyl-4-phenylpyridinium on glutathione in rat pheochromocytoma PC12 cells. Neurochem Int. 2000;36:489-97.

Sieb JP, Kraner S, Rauch M, Steinlein OK. Immature end-plates and utrophin deficiency in congenital myasthenic syndrome caused by epsilon-AChR subunit truncating mutations. Hum Genet. 2000;107:160-4.

Sieb JP, Kraner S, Schrank B, Reitter B, Goebel TH, Tzartos SJ, Steinlein OK. Severe congenital myasthenic syndrome due to homozygosity of the 1293insG epsilon-acetylcholine receptor subunit mutation. Ann Neurol. 2000;48:379-83.

Theuerkauf I, Lickfett L, Harbrecht U, Pohl C, Fischer H, Pfeifer U. Segmental hepatic vein thrombosis associated with heparin-induced thrombocytopenia II. Virchows Arch. 2000;436:88-91.

Tiemann K, Pohl C, Schlosser T, Goenechea J, Bruce M, Veltmann C, Kuntz S, Bangard M, Becher H. Stimulated acoustic emission: pseudo-doppler shifts seen during the destruction of nonmoving microbubbles. Ultrasound Med Biol. 2000;26:1161-7.

Tiemann K, Schlosser T, Pohl C, Bimmel D, Wietasch G, Hoeft A, Likungu J, Vahlhaus C, Kuntz S, Nanda NC, Becher H, Lüderitz B. Are microbubbles free flowing tracers through the myocardium? - Comparison of indicator-dilution curves obtained from dye-dilution and echocontrast using harmonic power Doppler imaging. Echocardiography. 2000;17:17-27.

Vielhaber S, Kudin A, Schröder R, Elger CE, Kunz WS. Muscle fibres: applications for the study of the metabolic consequences of enzyme deficiencies in skeletal muscle. Biochem Soc Trans. 2000;28:159-64.

Wiedemann FR, Vielhaber S, Schröder R, Elger CE, Kunz WS. Evaluation of methods for the determination of mitochondrial respiratory chain enzyme activities in human skeletal muscle samples. Anal Biochem. 2000;279:55-60.

Wüllner, U. Konzepte zur Pathogenese neurodegenerativer Erkrankungen. Nervenheilkunde. 2000;10:552-9.

Wüllner U, Weller M, Kornhuber J, Bornemann A, Schulz JB, Riederer P, Klockgether T. Altered expression of calcium- and apoptosis-regulating proteins in multiple system atrophy Purkinje cells. Mov Disord. 2000;15:269-75.

Zander T, Schwab S, Laufenberg I, Sieb JP. Immunohistochemical detection of complement factors: a reliable method for the diagnosis of myasthenia gravis. Nervenarzt. 2000;71:666-9.